In the summer of 1992, Coy Fitch M.D., chairman of the department of Medicine, sponsored the development of an academic division of dermatology. Prior to 1992, dermatology had been taught to students and resident physicians at Saint Louis University Medical Center by individual practitioners who donated their time.

For the first year, the new division was manned by four full-time physicians: Neal Penneys M.D., Ph.D. who came as chairperson and dermatopathologist; Craig Leonardi M.D. who came as clinical dermatologist and director of the molecular diagnostic laboratory; George Nahass M.D. who came as clinical dermatologist and director of the incipient residency program; and Elaine Siegfried M.D. who came as pediatric dermatologist. In the summer of 1993, Scott Fosko M.D. came as Mohs' surgeon and director of the surgical unit; and Dee Anna Glaser M.D. came as clinical and esthetic dermatologist. In the summer of 1997, Wayne A. Breer came as clinical dermatologist and dermatopathologist.

The faculty designed a residency program which received prompt provisional approval. The first two dermatology residents began their training in July of 1993. Since then, the program has admitted two-three residents yearly. After three and one half years, the division evolved into a free-standing Department of dermatology in January, 1996, as a recognition by the university of the group's academic and fiscal maturity. At the same time, the department moved to state-of-the-art facilities; clinical, academic and research spaces are at its current location in the Anheuser-Busch Institute.In November, 2009, our department opened a second facility at the Des Peres Medical Arts Pavilion II where patients can come to see our physicians in General Dermatology, Cosmetics, Phototherapy and Iontotherapy, and Mohs Surgery and Cutaneous Oncology. "One Practice, Two Locations".

The department is proud of its faculty, residents, staff, and facilities. Faculty serve as assistant editors, editorial board members, and active academic members of their subspecialties. Two of the faculty are listed in the text, Best Physicians in America. The department has developed as a premier clinical Dermatology program and provides patient services over a large portion of the Midwest region. Faculty and residents are active in clinical research and have established region and national reputations in their fields. Our residents have matriculated into clinical practice, academic positions as well as subspecialty fellowship programs.